I’ve been meaning to do this piece for some time now, but
with a new job, new colleagues, new office, and the dissertation load is
weighting in, it had been a struggle to find some spare time to actually put
this story in writing. Not that I have the time now, but I am right now trying
to find some (hopefully) bright inspirations for my dissertation, and in the
past I found it helpful to warm up by writing some light paragraphs.
Anyway, this story is about my involvement with National
Geographic’s Genographic project (www.genographic.com).
Apparently, NG has been conducting a global research for sometime as an attempt
to reveal human migration over the millenias, using the DNA to track down how
human populated the earth all the way back to the first migration out of africa
several thousands years ago.
Registering for the program was simple, just put some
personal information, submit the payment (I think it was around USD 200, but
consider it as a contribution to the science J),
and within 2 week I received a package containing DNA testing kit (some
peculiar looking swabs, not too different than your regular cotton swab, but
longer, and with detachable end, as well as some vials containing few
milimeters of unknown liquid, as well as a return envelope).
The instruction was to swab the inside of my cheek multiple
times, and drop the end of the swab into the vials containing the liquid, put
it back in the provided envelope, and send it back to Houston for analysis. Of
course several strict instructions also came along with the simple instruction:
don’t drink, don’t eat, don’t touch the swab with hand etc before taking the
sample. Good thing I received the package during the fasting months, so I got
on with it right after I woke up.
6-8 weeks later, the result came out, and it was quite
interesting. Apparently, today’s science is able to distinguish DNA mutation
from both paternal (my dad’s side) and maternal (my mom’s side). By the way,
theoretically they are able to track down where your ancestor are from
detecting some DNA mutation in your genes that are specific to some documented
mutations on their database, and by doing this they are able to at least tell
you where your ancestor came from, and even through which route your ancestry
line travelled all the way to Africa to, in my case, Bendungan Hilir, in
Jakarta, Indonesia.
Before I discuss the result, let me share you where my
parents came from.
Both of my mom and dad came from West Sumatra, normally
referred to as “minang” tribe. One of the few cultures in the world that using
matrilineal system. In simple word that would means we traced our ancestry
through maternal ancestor (from mother side), unlike the much more common
patrilineal descent. In fact, based on the good old wikipedia, Minang shared
this particular system with the North American Indian (Cheerokee, Choctaw,
Gitksan, Haida, Hopi, Iroquis, Lenape, Navajo, Tinglit),few tribes in South
India (Nairs of Kerala, and the Bunts and Billava of Karthataka), the Khasi,
Jaintia & Garo in Northeast India, The Basque of Spain and France (this is
new, I didn’t knew this fact before I looked it up at Wikipedia), the Tuaregs
(the blue man) in north africa, most Jewish communities, and the Serer tribe in
Senegal.
Naturally, I am a bit more familiar with my mom’s side of
the family ancistry than my dad’s, which is quite common for Minang people. In
fact, since I am a son in my family, according to the tradition, I don’t even
have the right on my daughter, for some things like proposing for marriage, and
in term of family inheritence as it all should pass to the daughter (my
sister). Good thing I married to a Javanese, and we are no longer in the olden
times. But that was just an interesting fact I think.
My mother side of the family has been living for generation
in a community called Tigo Tumpuak (3 layered, loosely translated), in a
village called Lima Kaum (five tribes, also loosely translated), near the city
of Batusangkar in West Sumatra. My grandfather from my mother side was a
schoolmaster at a local school, and my grandmother came from a familiy with
long history as a trader. In fact my mom’s grandfather (my great-great
grandfather) was doing well enough that he and his wife was able to undertake
the Hajj long before Indonesia’ independence in 1945 (you heard the stories,
took 2 years to do pilgrimage in olden times, etc etc). Interestingly, the
general area of Batusangkar was known as the ancient royal city of the Minangkabau
tribe. The Pagaruyung palace was less than 3 km from where my mother was born.
Back to my genographic result. The result was a lengthy
report composed of several different section. The first one was on the
“Ancestral Journey” that discuss how the DNA mutation found in my Genome can
track the journey took by my ancestor from Africa, which was estimated to
happened around 60,000 years ago. One particular point here is that all modern
human shared certain percentage of our DNA with Neanderthal, which in my case
is about 1.5%.
According to NG, the common direct ancestor to all women
alive today was born in East Africa around 180,000 years ago (or in their lingo
called the Haplogroup L3), which give birth to group of woman living in East
Africa or Asia (Haplogroup N) around 60,000 years ago.
Later on (aroiund 55,000 years ago), my ancestor starts to
move East (to West Asia) and branche out into Haplogroup R, then 3000 years
later, split again into B4’5 in Asia. One interesting note, some member of this
group was actually the ancestor of Northern America Indian, so this I around
the ice age I think where the land bridge (between Asia and America) was still
passable.
There several more sub branches discussed, but I’ll go
straight to when human started to populate Southeast Asia (Haplogroup P186)
which was around 28,000-41,000 years ago, then becoming M119 (31,500-39,500) in
SouthEast Asia.
This part is quite boring, since it is basically discuss
generic human population moving out from Africa to Asia, but what comes next is
a bit more interesting.
My Regional Ancestry (5,000-10,000 Years Ago)
If we averaged out human’s live average to around 60 years
old, then we are talking about 30,000 generation ago (wow that is a lot!).
Apparently my own genome are composed of the DNA of:
42% Northern
Asian
40%
Southeast Asian
10%
Southwest Asian
4% Oceanian
3%
Mediterranean
Wow!
I am not claiming that all Minang shared similar DNA as I,
this is only true for myself and 2 of my siblings. However, what striking are
the following:
1. The NG website also shared DNA composition of several
sampling population in the world. When I looked at the DNA of Chinese people
(sampled from the area around the modern days Beijing), I shared 82%
similarities with their DNA (which are the combination of mostly Northern Asian
and Southeast Asian, the further south it goes, such as in Vetnam, the larger
the Southeast Asian DNA become). So, enough about stupid racism, some people
will not like this, but hey, the old history lesson in school also mentioned
that the Malay came from Southern China. Myself, I actually don't doubt it just
by looking at my mom with her light skin and her slanted eyes that I also
shared.
2. When I looked at my youngest daughter, I can tell that
she shared some DNA with Southwest Asian (which means northern indian,
pakistan, tajiskistan, etc, whatever), which might also explain our curly hair
(despite of only 10% shared DNA with Southwest Asian)
3. Where’s the 4% Oceanian came from? The NG analysis shows
this came from my father side. I was puzzled by this as this DNA came from the
ocean fearing people in South Pacific (for example, the Papuan), but it also
highlight the “heatmap” or where the concentration of certain DNA can be found.
In this case, this DNA shared by most people in Madagaskar, and Sri Lanka.
Perhaps one of those ancient traders from Africa was my ancestor.
4. The 3% Mediterranean is rather confusing. Anyone can
guess? (hint, look at the wikipedia description I shared above)
All right, that’s pretty much all the information that
today’s science can provide now, but NG promises that they will update the
information from time to time. Some note, however:
1. I know that some former health minister of Indonesia in
the past has a stance against the “export” of DNA material overseas, but come
on! No research (at least publicly available one) is available here
domestically. We have the right to learn about our own genome I think right?
2. Due to the nature of the study, although NG says that my
genome also shared by less than 0.1% of the sampled population (meaning it
should be specific enough), I think the level of detail being shared apply to
my compatriots, or in other word I think most Indonesian/Malay shared similar
genetics composition as I, unfortunately I had only found 1 others Indonesian
that shared her result as well.
3. Was it worth it? It depends, but then again, I think it
was a worthy contribution to science (rather than using my tax money to drill
to the alleged ancient pyramid in west java, if you know what I mean)
Do tell me what do you think about this.
Interesting Don!
ReplyDeleteI don't know if you have read 'Guns, Germs and Steel' by Jared Diamond. This book describes human migration and some interesting fact about our cultural traces. Most interesting is its analysis on language. The language of Madagaskar is similar to Kahayan Dayak of Borneo - suggesting that some Dayak people managed to paddle thousand of kilometers on open ocean to reach Madagaskar thousans of years ago.
And something interesting: that the language of the Manggarai people of West Flores is similar to Minang language of West Sumatra!
Interesting article, glad you wrote it!
Cheers
Harnaz